基本信息
办公电话：021-51323185，17302118196
电子邮箱：alicexu@shutcm.edu.cn
通讯地址：上海市浦东新区蔡伦路1200号创新楼8楼801室
招生专业
| 院系名称 | 专业大类 | 一级学科 | 专业代码/专业名称 | 学位类型 | 招生类型 |
| 交叉科学研究院 | 医学 | 中药学 | 100800/中药学 | 学术学位 | 硕士 |
教育及任职经历
2006-2010 安徽师范大学生命科学学院 理学学士
2010-2013 华东师范大学理学院 理学硕士
2013-2018 上海交通大学化学化工学院 理学博士
2019-2021 上海交通大学化学化工学院 博士后
2022-至今 上海中医药大学交叉科学研究院 副研究员
研究方向
1、中草药免疫调节活性分子的发现、机制研究和纳米制剂开发。
2、纳米药物载体的生物学效应和体内命运。
近五年以第一负责人承担的科研课题与经费
序号 | 课题类型 | 项目时间 | 项目经费 （万元） | 备注 |
1 | 国家自然科学基金青年项目 | 2023.01-2025.12 | 30 | 主持 |
| 2 | 上海市地方高水平大学建设引进人才科研经费 | 2022.03-2028.03 | 50 | 主持 |
第一/通讯作者代表性论文
1. Li Xu+, Jiaqian Miao+, Danni Xu+, Xuan Mo, Junjie Wang, Sisi Chen, Bing Liu*, Guangbo Ge*, Xinyuan Zhu*, Hongping Deng*. Macrophage-targeted polysaccharide nano-immunomodulators with spatial- and time-programmed drug release for cancer therapy. Nano Today2026, 66,102893. (IF 10.9，Q1)
2. Jiaqian Miao, Yuxin Liu, Sisi Chen, Yinxuan Zhou, Jun Liu, Danni Xu, Xuan Mo, Junjie Wang, Qianli Zhu, Changqing Yu, Qian Qian, Hongping Deng*,Li Xu*, Guangbo Ge*. Self-assembled supramolecular nanoparticles of α-mangostin for targeted STING activation and enhanced tumor immunotherapy, Acta Pharmaceutica Sinica B 2026, DOI: 10.1016/j.apsb.2026.06.044. (IF: 14.6，Q1)
3. Qianli Zhu, Jiaqian Miao, Danni Xu, Minxia Zhang, Sisi Chen, Junjie Wang, Weiyi Chen, Jiaxuan Guo, Li Xu*, Sheng Ma*, Guangbo Ge*, Xinyuan Zhu*, Hongping Deng*. Cell selective STING-activating polysaccharide immunomodulators for cancer therapy.Adv. Mater. 2026, 38, e74178. (IF: 29.1，Q1)
4. Jiaqian Miao, Junjie Wang, Qianli Zhu, Xiangshu Cheng, Jingyi Ju, Meng Zhang, Jing Guo, Li Xu*, Guangbo Ge*, Ming Jin*, Hongping Deng*. A flexible antigen-presenting cell targeting lentinan immunomodulator promotes stimulator of interferon gene-driven cancer therapy, Carbohydrate Polymers, 2026, 386: 125427. (IF: 12.5，Q1)
5. Nanshan Ma, Sisi Chen, Jiaqian Miao, Ruoqi Zhao, Qinyu Gao, Minxia Zhang, XiyuHan, Yingxuan Zhou, Qing Xia*, Li Xu*, Jing Zhang*. From Juanbi Qianggu formula to a self-assembled nanodrug: identifyingmacrophage repolarization candidates and developing a carrier-free system for enhanced anti-inflammatory efficacy, J. Drug Deliv. Sci. Technol. 2026, 120,108183. (IF 5.3，Q1)
6. XuanMo, AnpingShen, Yicun Han, Li Xu*, Jiaqian Miao, DanniXu, QingJi, Yuelong Cao*, GuangboGe*, Xinyuan Zhu*, Hongping Deng*. Polysaccharide nanoadjuvants engineered via phenotype-specific nanoprobe-assisted phenotypic screen reprogram macrophage cell functions for cancer and rheumatoid arthritis therapy. ACS Nano2025, 19, 12920−12936. (IF 16.1，Q1)
7. Danni Xu , Jingxuan Ju , Wenchao Chen , Jiaqian Miao , Sisi Chen , Junjie Wang ,Li Xu*, Guangbo Ge*, Hongping Deng*. A light-controlled dextran nano-immunomodulator amplifies immunogenic cell death for cancer immunotherapy. Carbohydrate Polymers 2025, 366, 123885. (IF 12.5，Q1)
8. Jingxuan Ju+ , Danni Xu+ ,Li Xu*, Jun Liu, Hairong Zeng, Bei Zhao, Yuan Xiong, Yuhui Ma, Guangbo Ge*, Hongping Deng*. Polysaccharide nanoadjuvants with precise drug composition for enhanced STING-mediated APC activation. European Polymer Journal 2024, 217, 113333. (IF 5.8，Q1)
9. Li Xu+, Hongping Deng+, Liang Wu, Dali Wang, Leilei Shi, Qiuhui Qian, Xiangang Huang, Lijuan Zhu, Xihui Gao, Jiapei Yang, Yue Su*, Jing Feng*, and Xinyuan Zhu*. Supramolecular cyclic dinucleotide nanoparticles for STING-mediated cancer immunotherapy.ACS Nano 2023, 17(11), 10090–10103. (IF: 16.2，Q1)
10. Jingxuan Ju+, Danni Xu+, Xuan Mo, Jiaqian Miao,LiXu*, Guangbo Ge*, Xinyuan Zhu*, Hongping Deng*. Multifunctional polysaccharide nanoprobes for biological imaging. Carbohydrate Polymers2023, 317, 121048. (IF: 10.723，Q1)
11. Li Xu, Zhanying Ren, Guolin Li, Danni Xu, Jiaqian Miao, Jingxuan Ju, Xuan Mo, Xianghui Wang*, Hongping Deng*, Min Xu*. Liver-targeting MRI contrast agent based on galactose functionalized o-carboxymethyl chitosan. Front. Bioeng. Biotechnol. 2023,11:1134665. (IF: 5.1，Q1)
12. Hongping Deng*, Yan Chen, Li Xu*, Xuan Mo, Jingxuan Ju, Chunyang Yu*, Xinyuan Zhu. A Biomimetic Emitter Inspired from Green Fluorescent Protein. J. Phys. Chem. B 2022, 126 (43), 8771–8776. (IF: 2.8，Q3)
13. Yan Wu, Yu Huang, Chunlai Tu, Fengren Wu, Gangsheng Tong, Yue Su,Li Xu*,Xiaoqin Zhang*, Shuqiang Xiong*, Xinyuan Zhu. A mesoporous polydopamine nanoparticle enables highly efficientmanganese encapsulation for enhanced MRI-guided photothermal therapy, Nanoscale, 2021, 13(13): 6439-6446. (IF: 6.1，Q1)
14. Li Xu, Jiapei Yang, Leilei Shi, Chenwei Wu, hua Jin, Xin Jin, Yue Su* , Yumin Liu, and Xinyuan Zhu*. Short-term urea cycle inhibition in rat liver cells induced by polyethylene glycol, Biomaterials Science, 2018, 6, 2896-2904. (IF: 6.2，Q1)
15. Chenwei Wu+, Li Xu+, Leilei Shi, Xihui Gao, Jing Li, Xinyuan Zhu* , Chuan Zhang*, Supramolecularly self-assembled nano-twin drug for reversing multidrug resistance, Biomaterials Science, 2018, 6, 2261-2269. (IF: 6.2，Q1)
17. Li Xu, Jiapei Yang, Bai Xue, Chuan Zhang*, Leilei Shi, Chenwei Wu, Yue Su, Xin Jin, Yumin Liu*, Xinyuan Zhu* . Molecular insights for the biological interactions between polyethylene glycol and cells, Biomaterials, 2017, 147, 1-13. (IF: 13.1， Q1)