陈红专 教授

发布者：交叉科学研究院-01发布时间：2022-07-06浏览次数：7624

招生专业

 

院系名称专业大类一级学科专业代码/专业名称学位类型招生类型
交叉科学研究院医学中药学100800/中药学学术学位博士/硕士
交叉科学研究院医学中药学105600/中药学专业学位硕士


教育及任职经历

1978-1983    浙江医科大学 临床医学专业                  获学士学位

1983-1986    上海第二医科大学药理学专业                获硕士学位

1987-1990    上海第二医科大学药理学专业                获博士学位

1993-1995    法国国立健康与卫生研究院（INSERM）博士后

1998-1999    法国里昂第一大学临床药理学                高级访问学者

任职经历

现任上海中医药大学副校长，上海交通大学医学院-中国科学院神经科学所脑疾病研究中心主任，上海市转化医学协同创新中心主任，上海市高校系统药理学重点实验室主任，上海市“药学”一流学科带头人。担任国务院学科评议组成员、国家药品审评专家、国家自然科学基金委二审专家、上海市药学会理事长、上海市学位委员会（药学）召集人等，同时担任国际著名专业期刊Mol Pharmacol、CNS Neuroscience and Therapeutics、Acta Pharmacol Sin、Transl Neurodegener等编委。现任全国政协委员、浦东新区人大副主任；民盟上海市委副主委、民盟浦东新区主委；上海市第三检察院特邀监督员。

目前以第一负责人承担的科研课题与经费

序号

课题类型

项目时间

项目经费

（万元）

备注

1

上海市中药化学生物学前沿研究基地

2021.01-2025.12

2500

主持

代表性文章（第一/通讯作者）

1. Lai X, Liu XL, Pan H, Zhu MH, Long M, Yuan Y, Zhang Z, Dong X, Lu Q, Sun P, Lovell JF, Chen HZ, Fang C*. Light-Triggered Efficient Sequential Drug Delivery of Biomimetic Nanosystem for Multimodal Chemo-, Antiangiogenic, and Anti-MDSC Therapy in Melanoma. Adv Mater. 2022, 34(10):e2106682. (IF 32.086)

2. Mu Y,# Zhang L#*, Hu J#, Zhou J, Lin HW, He C, Chen HZ*, Zhang L*. A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat Chem Biol. 2022 Jul;18(7):733-741. (IF 16.174)

3. Feng HY, Yuan Y, Zhang Y, Liu HJ, Dong X, Yang SC, Liu XL, Lai X, Zhu MH, Wang J, Lu Q, Lin Q, Chen HZ, Lovell JF, Sun P*, Fang C*. Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Orthotopic Colorectal Tumor Model. Nanomicro Lett. 2021,13(1):145. (IF 23.655)

4. Yang F#, Brady SW#, Tang C#, Sun H#, Du L#, Barz MJ, Ma X, Chen Y, Fang H, Li X, Kolekar P, Pathak O, Cai J, Ding L, Wang T, von Stackelberg A, Shen S, Eckert C, Klco JM, Chen H, Duan C, Liu Y*, Li H*, Li B*, Kirschner-Schwabe R, Zhang J, Zhou BS. Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse. Nat Cancer. 2021,2(8):819-834. (IF 23.177)

5.  Liu XL, Dong X, Yang SC, Lai X, Liu HJ, Gao Y, Feng HY, Zhu MH, Yuan Y, Lu Q, Lovell JF, Chen HZ*, Fang C*. Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy. Adv Sci (Weinh). 2021 Mar 1;8(8):2003679. (IF 17.521)

6.  Zhang KR#, Zhang YF#, Lei HM#, Tang YB#, Ma CS, Lv QM, Wang SY, Lu LM, Shen Y*, Chen HZ*, Zhu L*. Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer. Sci Transl Med. 2021,13(614):eabg6428. (IF 19.319)

7.  Shen YW, Zhou YD, Chen HZ, Luan X*, Zhang WD*. Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity. Trends Cancer. 2021, 7(6):511-524. (IF 19.161)

8.  Zhou J#, Zhang L#, Zeng L#, Yu L#, Duan Y#, Shen S#, Hu J, Zhang P, Song W, Ruan X, Jiang J, Zhang Y, Zhou L, Jia J, Hang X, Tian C, Lin H, Chen HZ*, Cronan JE*, Bi H*, Zhang L*. Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis. Nat Commun. 2021,12(1):6932. (IF 17.692)

9.  Chen L#, Song Q#, Chen Y, Meng S, Zheng M, Huang J, Zhang Q, Jiang J, Feng J, Chen HZ, Jiang G*, Gao X*. Tailored Reconstituted Lipoprotein for Site-Specific and Mitochondria-Targeted Cyclosporine A Delivery to Treat Traumatic Brain Injury. ACS Nano. 2020,14(6):6636-6648. (IF 18.027)

10. Zhang Q, Song Q, Gu X, Zheng M, Wang A, Jiang G, Huang M, Chen H, Qiu Y, Bo B, Tong S, Shao R, Li B, Wang G, Wang H, Hu Y, Chen HZ*, Gao X*. Multifunctional Nanostructure RAP-RL Rescues Alzheimer's Cognitive Deficits through Remodeling the Neurovascular Unit. Adv Sci (Weinh). 2020 Dec 10;8(2):2001918. (IF 17.521)

11.  Jiang G, Chen H, Huang J, Song Q, Chen Y, Gu X, Jiang Z, Huang Y, Lin Y, Feng J, Jiang J, Bao Y, Zheng G, Chen J*, Chen H*, Gao X*. Tailored Lipoprotein-Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor-Stimulated Macropinocytosis. Adv Sci (Weinh). 2020 Jan 20;7(5):1903290. (IF 17.521)

12. Huang K#, Liang Q#, Zhou Y#, Jiang LL, Gu WM, Luo MY, Tang YB, Wang Y, Lu W, Huang M, Zhang SZ, Zhuang GL, Dai Q, Shen QC, Zhang J, Lei HM, Zhu L, Ye DY, Chen HZ*, Zhou L*, Shen Y*. A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer. Cell Metab. 2019,30(6):1107-1119.e8. (IF 31.373)

13. Luan X, Guan YY, Liu HJ, Lu Q, Zhao M, Sun D, Lovell JF, Sun P, Chen HZ*, Fang C*. A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia. Adv Sci (Weinh). 2018 May 28;5(8):1800034. (IF 17.521)

14. Zhao WS#, Wang J#, Ma XJ#, Yang Y, Liu Y, Huang LD, Fan YZ, Cheng XY, Chen HZ, Wang R*, Yu Y*. Relative motions between left flipper and dorsal fin domains favour P2X4 receptor activation. Nat Commun. 2014 Jun 19;5:4189. (IF 17.694)