招生专业
院系名称 | 专业大类 | 一级学科 | 专业代码/专业名称 | 学位类型 | 招生类型 |
交叉科学研究院 | 医学 | 中药学 | 100800/中药学 | 学术学位 | 博士/硕士 |
交叉科学研究院 | 医学 | 中药学 | 105600/中药学 | 专业学位 | 硕士 |
教育及任职经历
1984.09-1988.07 第二军医大学药学院 获学士学位
1988.09-1991.07 第二军医大学药学院 获硕士学位
1995.09-1998.09 上海医药工业研究院 获博士学位
任职经历
担任第十届国家药典委员会天然药物专业委员会副主任委员,世界中医药学会联合会中药化学专业委员会副理事长,上海市药学会天然药物化学专业委员会副主任委员,国家中药标准化工程中心副主任,上海活性天然产物制备工程中心主任,《中国药典》英文版副主编。先后担任Journal of Pharmaceutical and Biochemical Analysis, Planta Medica, Fitoterapia等多本国际学术期刊和中文核心刊物《药学学报》、《中国中药杂志》的编委。
目前以第一负责人承担的科研课题与经费
序号 | 课题类型 | 项目时间 | 项目经费 (万元) | 备注 |
1 | 上海市进一步加快中医药传承创新发展三年行动计划 | 2021.09-2023.12 | 1309.44 | 主持 |
2 | 国家中医药多学科交叉创新团队项目 | 2021.01-2023.12 | 972 | 主持 |
代表性文章(第一/通讯作者)
1. Qi S#, Guan X#, Zhang J#, Yu D, Yu X, Li Q, Yin W, Cheng XD*, Zhang WD*, Qin JJ*. Targeting E2 ubiquitin-conjugating enzyme UbcH5c by small molecule inhibitor suppresses pancreatic cancer growth and metastasis. Mol Cancer. 2022 Mar 10;21(1):70. (IF 41.44)
2. Shen YW, Zhou YD, Chen HZ, Luan X*, Zhang WD*. Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity. Trends Cancer. 2021 Jun;7(6):511-524. (IF 19.161)
3. Luan X#, Wu Y#, Shen YW, Zhang H, Zhou YD, Chen HZ, Nagle DG*, Zhang WD*. Cytotoxic and antitumor peptides as novel chemotherapeutics. Nat Prod Rep. 2021 Jan 1;38(1):7-17. (IF 15.111)
4. Huang R#, Zhang L#, Jin J#, Zhou Y, Zhang H, Lv C, Lu D, Wu Y, Zhang H, Liu S, Chen H*, Luan X*, Zhang WD*. Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction. Acta Pharm Sin B. 2021 Nov;11(11):3481-3492. (IF 14.903)
5. Zheng N, Gu Y, Hong Y, Sheng L, Chen L, Zhang ,Hou J, Zhang WD, Jia W*, Li H*. Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid. J Pharm Anal. 2020; (IF 14.026)
6. Li S, Si C, Zhang WD*, Hu HG*.Stapled Helical Peptides Bearing Different Anchoring Residues. Chem Rev, 2020, 120(18):10079-10144. (IF 72.087)
7. Shen YW, Zhou YD, Luan X*, Zhang WD*. Blocking CTGF-Mediated Tumor-Stroma Interplay in Pancreatic Cancer. Trends Mol Med. 2020 Dec;26(12):1064-1067. (IF 15.272)
8. Jin J#, Qiu S#, Wang P, Liang X, Huang F, Wu H, Zhang B, Zhang WD, Tian X, Xu R*, Shi H*, Wu X. Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming. J Exp Clin Cancer Res. 2019;38(1):377. (IF 12.658)
9. Bai F#, Liu K#, Li H#, Wang J, Zhu J, Hao P, Zhu L, Zhang S, Shan L, Ma W, Bode A, Zhang WD*, Li H*, Dong Z*. Veratramine modulates AP-1-dependent gene transcription by directly binding to programmable DNA. Nucleic Acids Res. 2018;46(2):546-557. (IF 19.160)
10. Qu Y, Olsen JR, Yuan X, Cheng PF, Levesque MP, Brokstad KA, Hoffman PS, Oyan AM, Zhang WD*, Kalland KH*, Ke X*. Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer. Nat Chem Biol. 2018 Jan;14(1):94-101. (IF 16.174)
11. Cui C, Zhou X, Zhang WD*, Qu Y*, Ke X*. Is β-Catenin a Druggable Target for Cancer Therapy?. Trends Biochem Sci. 2018;43(8):623-634. (IF 14.264)
12. Zhang Z#, Wang J#, Li J#, Yang F, Liu G, Tang W, He W, Fu JJ, Shen YH*, Li A*, Zhang WD*. Total Synthesis and Stereochemical Assignment of Delavatine A: Rh-Catalyzed Asymmetric Hydrogenation of Indene-Type Tetrasubstituted Olefins and Kinetic Resolution through Pd-Catalyzed Triflamide-Directed C-H Olefination. J Am Chem Soc. 2017 Apr 19;139(15):5558-5567. (IF 16.383)
13. Li X, Yang X, Liu Y, Gong N, Yao W, Chen P, Qin J, Jin H, Li J, Chu R, Shan L, Zhang R, Zhang WD*, Wang H*. Japonicone A suppresses growth of Burkitt lymphoma cells through its effect on NF-κB. Clin Cancer Res. 2013;19(11):2917-2928. (IF 13.801)