吴涛 研究员

发布者:吴涛发布时间:2022-06-21浏览次数:1656

吴涛

医学博士,研究员,博士生导师

 

基本信息

办公电话:021-51322748

电子邮箱:tw827@shutcm.edu.cn or wutao001827@163.com

通讯地址:上海市浦东新区蔡伦路1200号2号楼2311室

 

研究方向

中医药防治慢性肝病的基础与临床研究

 

招生专业

院系名称

专业大类

一级学科

专业代码/专业名称

学位类型

招生类型

交叉科学研究院

医学

中医学

100506/中医内科学

学术学位

硕士

 

教育及任职经历

   

        2021/01-至今,上海中医药大学,交叉科学研究院,研究员

        2016/11-2017/04,上海交通大学附属第六人民医院,转化医学研究中心,访问学者

        2015/01-2020/12,上海中医药大学,交叉科学研究院,副研究员

        2013/11-2014/10,美国夏威夷大学,癌症研究中心,访问学者

        2009/12-2014/12,上海中医药大学,中医方证与系统生物学研究中心,助理研究员

        2008/08-2009/11,上海中医药大学,中医方证与系统生物学研究中心,研究实习员

        2010/09 - 2015/07,上海中医药大学,中医内科学,博士

        2005/09 - 2008/07,上海中医药大学,中医内科学,硕士

        1997/09 - 2002/07,江西中医学院,中西医结合,学士


近五年以第一负责人承担的科研课题与经费

序号

项目来源

项目名称

起止时间

经费(万元)

1

上海中医药大学杏林百人计划

降脂颗粒有效成分改善NASH的机理研究

2021/01-2023/12

15

2

国家自然科学基金面上项目

清肝活血方通过LXR-LPCAT3信号通路抑制内质网应激改善酒精性肝病的机制研究

2019/01-2022/12

57

3

上海市人才发展基金

LPCAT在NASH中的关键作用及降脂颗粒干预研究

2017/09-2020/08

20

 

第一/通讯作者代表性论文

(1)        Qiaoli Sun, Yingjue Tang, Liang Dai, Zhipeng Tang, Wenjun Zhou, Tao Wu*, Guang Ji*. Serum Bile Acid Metabolites Predict the Therapeutic Effect of Mesalazine in Patients with Ulcerative Colitis. Journal of Proteome Research 2023 10.1021/acs.jproteome.2c00820IF=5.370

(2)        Junmin Wang, Yifei Lu, Caiyun Zhang, Shuxia Tian, Hongjiao Xiang, Peilun Ding, Junming Chen*, Guang Ji*, Tao Wu*. Qinggan Huoxue Recipe attenuates Alcoholic Liver Disease by suppressing PI3K/AKT signaling pathway based on network pharmacology. International Journal of Medical Sciences 2023; 20(3): 346-358IF=3.642

(3)        Junmin Wang#, Qiaoli Sun#, Ying Gao#, Hongjiao Xiang, Caiyun Zhang, Peilun Ding, Tao Wu*, Guang Ji*. Metabolomics window into the diagnosis and treatment of inflammatory bowel disease in recent 5 years. International Immunopharmacology. Volume 113, Part B, 2022, 109472IF=5.714

(4)        Peilun Ding#, Ying Gao#, Junmin Wang, Hongjiao Xiang, Caiyun Zhang, Lei Wang*, Guang Ji*, Tao Wu*. Progress and challenges of multidrug resistance proteins in diseases. American Journal of Cancer Research2022;12(10): 4483-4501 (IF=5.942)

(5)        Guang Ji*, Guoxiang Xie, Tao Wu* and Yunping Qiu. Editorial: Nonalcoholic fatty liver disease: From pathogenesis to phytomedicine based on omics technology. Frontiers in Pharmacology 2022, 13: 1062979. (IF=5.988)

(6)        Yifei Lu, Mingmei Shao, Caiyun Zhang, Hongjiao Xiang, Junmin Wang, Tao Wu* and Guang Ji*. Kaempferol attenuates nonalcoholic steatohepatitis by regulating serum and liver bile acid metabolism.Frontiers in Pharmacology 2022,13: 946360 (IF=5.988)

(7)        Xiazhen Nong#, Caiyun Zhang#, Junmin Wang, Peilun Ding, Guang Ji*, Tao Wu*. The mechanism of branched-chain amino acid transferases in different diseases: research progress and future prospects. Frontiers in Oncology 2022,12: 988290 (IF=5.738)  

(8)     Mingmei Shao, Lu Yifei, Hongjiao Xiang, Junmin Wang, Guang Ji* and Tao Wu*. Application of Metabolomics in the Diagnosis of Non-alcoholic Fatty Liver Disease and the Treatment of Traditional Chinese Medicine.Frontiers in Pharmacology 2022,13: 971561. (IF=5.988)  

(9)        Ming-Mei Shao#, Hong-Jiao Xiang#, Hao Lu, Pei-Hao Yin, Guo-Wen Li, Yun-Man Wang, Lin Chen, Qing-Guang Chen, Cheng Zhao, Qun Lu, Tao Wu*, Guang Ji*. Potential metabolite markers of peripheral neuropathy in Chinese patients with type 2 diabetes. American Journal of Translational Research 2022;14(8):5420-5440 (IF=3.94) 

(10)    Hongyu Chen, Junmin Wang, Caiyun Zhang, Peilun Ding, Shuxia Tian, Junming  Chen*, Guang Ji *, Tao Wu *. Sphingosine 1-phosphate receptor, a new therapeutic direction in different diseases. Biomedicine & Pharmacotherapy 2022; 153, 113341: 1-10 (IF=7.419) 

(11)    Tao Wu, Xiaojiao Zheng, Ming Yang, Aihua Zhao, Hongjiao Xiang, Tianlu Chen, Wei Jia*, Guang Ji*. Serum amino acid profiles predict the development of hepatocellular carcinoma in patients with chronic HBV infection. ACS omega 2022 Apr 25;7(18):15795-15808 (IF=3.512)

(12)    Yifei Lu, Mingmei Shao, Hongjiao Xiang, Junmin Wang, Guang Ji *, Tao Wu*. Qinggan Huoxue Recipe alleviates chronic alcoholic liver injury by suppressing endoplasmic reticulum stress through LXR-LPCAT3. Frontiers in Pharmacology. 2022; 13:824185. (IF=5.988) 

(13)    Yirong Wang#, Junmin Wang#, Hongjiao Xiang, Peilun Ding, Tao Wu*, Guang Ji *. Recent update on application of dihydromyricetin in metabolic related diseases. Biomedicine & Pharmacotherapy 2022; 148, 112771: 1-9 (IF=7.419)

(14)    Kaixu Yang#, Junmin Wang#, Hongjiao Xiang, Peilun Ding, Tao Wu*, Guang Ji*. LCAT- targeted therapies: Progress, failures and future. Biomedicine & Pharmacotherapy. 2022 Feb 1; 147: 112677, 1-13 (IF=7.419)

(15)    Qinyi Wang#, Junmin Wang#, Hongjiao Xiang, Peilun Ding, Tao Wu*, Guang Ji*. The biochemical and clinical implications of phosphatase and tensin homolog deleted on chromosome ten in different cancers. Am J Cancer Res 2021; 11(12): 5833–5855. (IF=6.166)

(16)    Hongjiao Xiang, Zecheng Wu, Junmin Wang, Tao Wu*. Research progress, challenges and perspectives on PNPLA3 and its variants in Liver Diseases. J Cancer 2021; 12(19):5929-5937. (IF=4.207)

(17)    Junmin Wang, Hongjiao Xiang, Yifei Lu, Tao Wu* and Guang Ji*. New progress in drugs treatment of diabetic kidney disease. Biomedicine & Pharmacotherapy 141 (2021) 111918: 1-18 (IF=6.529)  

(18)    Hongjiao Xiang#, Mingmei Shao#, Yifei Lu, Junmin Wang, Tao Wu* and Guang Ji*. Kaempferol alleviates steatosis and inflammation during early non-alcoholic steatohepatitis associated with liver X receptor α-lysophosphatidylcholine acyltransferase 3 signaling pathway. Frontiers in Pharmacology 2021 Jun 28; 12: 690736 (IF=5.810)

(19)    Junmin Wang, Hongjiao Xiang, Yifei Lu, Tao Wu* and Guang Ji*. The Role and Therapeutic Implication of CPTs in Fatty Acid Oxidation and Cancers Progression. Am J Cancer Res 2021 Jun 15;11(6):2477-2494 (IF=6.166)

(20)    Tao Wu, Ming Yang, Hanchen Xu, Lei Wang, Huafeng Wei, Guang Ji*. Serum Bile Acid Profiles Improve Clinical Prediction of Nonalcoholic Fatty Liver in T2DM patients. Journal of Proteome Research2021, 20, 8, 3814–3825 (IF=4.466) (Supplementary封面论文

(21)    Hongjiao Xiang#, Shengjie Jin#, Fenglang Tan, Yifan Xu, Yifei Lu, Tao Wu*. Physiological functions and therapeutic applications of neutral sphingomyelinase and acid sphingomyelinase. Biomedicine & Pharmacotherapy139(2021)111610:1-13  (IF=6.529)

(22)    Junmin Wang, Hongjiao Xiang, Yifei Lu, Tao Wu*. Role and clinical significance of TGF‑β1 and TGF‑βR1 in malignant tumors (Review). International Journal of Molecular Medicine 47, no. 4 (2021): 55. (IF=4.103)

(23)    Xinyi Chen, Hongjiao Xiang, Shiyu Yu, Yifei Lu, Tao Wu*. Research progress in the role and mechanism of Cadherin-11 in different diseases. Journal of Cancer 2021;12(4):1190-1199. (IF=4.207)

(24)    Chenze Shi, #, Lei Wang, #, Kejun Zhou, Mingmei Shao, Yifei Lu, Tao Wu*. Targeted metabolomics identifies differential serum and liver amino acids biomarkers in rats with alcoholic liver disease. Journal of nutritional science and vitaminology66,543-551,2020  (IF=2.003)

(25)    Yifei Lu, Mingmei Shao, Hongjiao Xiang, Peiyong Zheng, Tao Wu* and Guang Ji*. Integrative transcriptomics and metabolomics explore the mechanism of kamepferol on improving NASH.Food & Function, 2020,11, 10058 - 10069 (IF=5.396)

(26)    Zixiang Ye, Yifei Lu and Tao Wu*. The impact of ATP-binding cassette transporters on metabolic diseases. Nutrition & Metabolism (2020) 17:61:1-14 (IF=3.211) 

(27)    Mingmei Shao#, Hao Lu#, Ming Yang , Yang Liu, Peihao Yin, Guowen Li, Yunman Wang, Lin Chen, Qingguang Chen, Cheng Zhao, Qun Lu , Tao Wu*, and Guang Ji*. Serum and urine metabolomics reveal potential biomarkers of T2DM patients with nephropathy. Annals of Translational Medicine 2020;8(5):199  (IF=3.297)

(28)    Zixiang Ye, Linxiu Yue, Jiachen Shi, Mingmei Shao, Tao Wu*. Role of IDO and TDO in Cancers and Related Diseases and the Therapeutic Implications.Journal of Cancer 2019; 10(12): 2771-2782. (IF=3.259)

(29)    Jie Ren#, Yifei Lu#, Yanhong Qian, Bozhou Chen, Tao Wu* and Guang Ji*. Recent progress regarding kaempferol for the treatment of various diseases (Review). Exp Ther Med 18: 2759-2776, 2019 (IF=1.785)ESI高被引论文

(30)    Tao Wu, Xiaojiao Zheng, Ming Yang, Aihua Zhao, Meng Li, Tianlu Chen, Jun Panee, Wei Jia*, Guang Ji*. Serum lipid alterations identified in chronic hepatitis B, hepatitis B virus-associated cirrhosis and carcinoma patients. Sci Rep. 2017 Feb 15;7:42710. (IF=4.259)